Heart failure (HF) is a major public health issue in both developed and developing countries 1
. In the last few decades, advances in drug therapy, implantable cardioverter defibrillators (ICD) and cardiac resynchronisation therapy – in the earlier phases - as well as mechanical circulatory support with left ventricular assist devices (LVAD) and heart transplantation – when clinical conditions become advanced and recalcitrant - have contributed to improvements in the prognosis of patients with HF and reduced ejection fraction (HFrEF) 1Join us for free and access thousands of articles from EuroIntervention, as well as presentations, videos, cases from PCRonline.com