Objective
to determine whether 1-month DAPT followed by aspirin monotherapy after polymer-free drug-coated stend (PF-DCS) is noninferior to 6 to 12 months of DAPT after biodegradable polymer-drug eluting stent (BP-DES) implantation
Study
multicentre, open-label noninferiority randomised trial (non-inferiority margin 3.0%)
Population
patients with non emergent PCI
Endpoints
composite of cardiac death, MI targe-vessel revascularisation, stroke, or major bleeding at 1 year
Conclusion
one-month DAPT followed by aspirin monotherapy was non-inferior to 6-12 month DAPT for 1 year MACE or major bleeding. Note: the two different stent platforms may have impacted on the outcome of this study
Hong et al. J Am Coll Cardiol. Intv. 2021;14:1801-11