Objective
to report the 5-year clinical outcome of clopidogrel monotherapy following 1 month DAPT with aspirin monotherapy following 12 months DAPT after PCI
Study
multicentre, open-label, randomised trial
Population
patients with successful PCI using cobalt-chromium everolimus eluting stents
Endpoints
net adverse clinical events as composite of cardiovascular events (cardiac death, MI, stent thrombosis, stroke) and TIMI major/minor bleeding at 5 years
Conclusion
clopidogrel monotherapy was noninferior but not superior to aspirin monotherapy during 5-years follow-up after successful PCI
Watanabe et al. J Am Coll Cardiol. 2024;83:17-31