Objective
to evaluate 5-year clinical and haemodynamic outcomes with TAVI vs surgery in low-risk patients with severe aortic stenosis
Study
international, multicentre, open-label, randomised controlled trial at 86
Population
patients with severe tri-leaflet aortic valve stenosis, a low predicted risk of death (<3%) following surgical aortic valve replacement as assessed by a local multidisciplinary heart team, and anatomic suitability for both TAVI and surgery
Endpoints
5-year rates of all-cause mortality or disabling stroke
Conclusion
At 5 years, patients with severe aortic stenosis who were treated with either TAVI or surgery had comparable rates of all-cause mortality or disabling stroke.
Forrest et al. J Am Coll Cardiol. 2025:S0735-1097(25)05335-5.