1. Drug-eluting and bare metal stents

Amphilimus- versus zotarolimus-eluting stents in patients with diabetes mellitus and coronary artery disease

SUGAR
Objective
to compare the Cre8 EVO stent to the Resolute Onyx stent in patients with diabetes and CAD
Study
multicentre, open-label, randomised controlled non-inferiority trial
Population
diabetic cases with ≥50% stenosis in coronary lesions suitable for PCI
Endpoints
target lesion failure, which included cardiac death, target-vessel myocardial infarction, or clinically indicated target-lesion revascularisation
Conclusion
in patients with diabetes undergoing PCI, Cre8 EVO stents were non-inferior to Resolute Onyx stents in terms of composite outcome of target lesion failure
Romaguera et al. Eur Heart J. 2022; 43:1320-1330
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