Objective
to assess the 12-month clinical outcomes of angiography-derived FFR or optimisation of stent implantation for PCI treatment of coronary stenosis
Study
investigator-initiated multicentre randomised non-inferiority trial
Population
patients with ischaemic heart disease and at least one 50% coronary stenosis
Endpoints
composite of death, MI or revascularisation at 12 months


Conclusion
An angiography-derived, FFR-guided PCI strategy was non-inferior to IVUS guidance.
Hu et al. Lancet. 2025 Mar 28:S0140-6736(25)00504-5.