Objective
to compare saphenous vein graft patency after ticagrelor, aspirin or both
Study
multicentre, open-label, randomised controlled trial
Population
patients within 24 hours of elective CABG without any indication for DAPT or high bleeding risk
Endpoints
saphenous vein graft patency at 1 year
Conclusion
Ticagrelor plus aspirin significantly improved graft patency at 1 year compared with aspirin alone. The study was not powered to detect differences in MACE or major bleeding
Zhao et al. JAMA. 2018;319:1677-86