Objective
to report the 5-year clinical outcome of guided PCI using instantaneous wave-free ratio (i-FR) compared to fractional flow reserve (FFR)
Study
multicentre, open-label randomised trial
Population
patients with chronic or acute coronary syndromes (only non-culprit lesions were physiologically assessed). Threshold important stenosis iFR â¤0.80
Endpoints
MACE: all-cause death, MI or unplanned revascularisation at 5 years
Conclusion
the 5-year adverse clinical outcomes of i-FR used as physiological assessment of coronary lesions compared to FFR among patients with chronic and acute coronary syndromes are not different
Götberg et al. J Am Coll Cardiol. 2022;79:965-74