Objective
to report the 5-year clinical outcomes of PCI guided by fractional flow reserve (FFR) or instantaneous wave-free ratio (iFR)
Study
international multicentre randomised trial
Population
patients with CAD and at least 1 native coronary stenosis
Endpoints
MACE as a composite of all-cause death, MI and resvascularisation at 5 years
Conclusion
At 5-year follow-up, an iFR-based strategy was not different from an FFR strategy to guide PCI in terms of MACE.
Escaned et al. JAMA Cardiol. 2025;10(1):25-31.