Objective
to compare the efficacy of ticagrelor and aspirin after CABG surgery
Study
prospective, multicentre, placebo-controlled, randomised trial
Population
patients age >18 with ACS or stable CAD scheduled for CABG surgery
Endpoints
composite of cardiovascular death, myocardial infarction (MI), repeat revascularisation, and stroke 12 months after CABG
Conclusion
no significant difference in major cardiovascular events or major bleeding could be demonstrated though the trial was prematurely terminated and underpowered
Schunkert et al. Eur Heart J. 2019;40;2432-40