2. PCI for STEMI

Sirolimus versus Everolimus eluting stents for STEMI

BIOSTEMI 5 years
Objective
to compare the 5-year clinical outcomes after primary PCI with biodegradable polymer sirolimus-eluting stents (BP-SES) or durable polymer everolimus-eluting stents (DP-EES)
Study
investigator-initiated, multicentre extension randomised study
Population
patients with STEMI undergoing primary PCI
Endpoints
target lesion failure as composite of cardiac death, re-MI or target lesion revascularisation within 5 years
Conclusion
biodegradable polymer SES was superior to durable polymer EES in patients undergoing PCI for STEMI at 5 years of follow-up
Iglesias et al. Lancet. 2023; October
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